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P2Y nucleotide receptors: Promise of therapeutic applications

Extracellular nucleotides, such as ATP and UTP, have distinct signaling roles through a class of G protein-coupled receptors, termed P2Y. However, the receptor ligands are typically charged molecules of low bioavailability and stability in vivo. Recent progress in the development of selective agonis...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Jacobson, Kenneth A., Boeynaems, Jean-Marie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920619/
https://ncbi.nlm.nih.gov/pubmed/20594935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2010.05.011
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