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In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons

Protein translation has been implicated in different forms of synaptic plasticity but direct in situ visualization of new proteins is limited to one or two proteins at a time. Here we describe a metabolic labeling approach based upon incorporation of non-canonical amino acids into proteins followed...

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Detalhes bibliográficos
Main Authors: Dieterich, Daniela C., Hodas, Jennifer J.L., Gouzer, Geraldine, Shadrin, Ilya Y., Ngo, John T., Triller, Antoine, Tirrell, David A., Schuman, Erin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920597/
https://ncbi.nlm.nih.gov/pubmed/20543841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2580
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