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Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT)

In both normal and pathological states, cells respond rapidly to environmental cues by synthesizing new proteins. The selective identification of a newly synthesized proteome has been hindered by the basic fact that all proteins, new and old, share the same pool of amino acids and thus are chemicall...

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Detalhes bibliográficos
Main Authors: Dieterich, Daniela C., Link, A. James, Graumann, Johannes, Tirrell, David A., Schuman, Erin M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1480433/
https://ncbi.nlm.nih.gov/pubmed/16769897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601637103
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