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Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT)

In both normal and pathological states, cells respond rapidly to environmental cues by synthesizing new proteins. The selective identification of a newly synthesized proteome has been hindered by the basic fact that all proteins, new and old, share the same pool of amino acids and thus are chemicall...

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Hlavní autoři: Dieterich, Daniela C., Link, A. James, Graumann, Johannes, Tirrell, David A., Schuman, Erin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1480433/
https://ncbi.nlm.nih.gov/pubmed/16769897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601637103
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