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The evolutionary significance of copy number variation in the human genome
Copy number variation provides the raw material for gene family expansion and diversification, which is an important evolutionary force. Moreover, copy number variants (CNVs) can influence gene transcriptional and translational levels and have been associated with complex disease susceptibility. The...
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| Autore principale: | |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
S. Karger AG
2009
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920192/ https://ncbi.nlm.nih.gov/pubmed/19287166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000184719 |
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