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The evolutionary significance of copy number variation in the human genome

Copy number variation provides the raw material for gene family expansion and diversification, which is an important evolutionary force. Moreover, copy number variants (CNVs) can influence gene transcriptional and translational levels and have been associated with complex disease susceptibility. The...

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Detalhes bibliográficos
Autor principal: Perry, G.H.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920192/
https://ncbi.nlm.nih.gov/pubmed/19287166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000184719
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