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The evolutionary significance of copy number variation in the human genome

Copy number variation provides the raw material for gene family expansion and diversification, which is an important evolutionary force. Moreover, copy number variants (CNVs) can influence gene transcriptional and translational levels and have been associated with complex disease susceptibility. The...

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Détails bibliographiques
Auteur principal: Perry, G.H.
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920192/
https://ncbi.nlm.nih.gov/pubmed/19287166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000184719
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