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The evolutionary significance of copy number variation in the human genome

Copy number variation provides the raw material for gene family expansion and diversification, which is an important evolutionary force. Moreover, copy number variants (CNVs) can influence gene transcriptional and translational levels and have been associated with complex disease susceptibility. The...

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Bibliografiske detaljer
Hovedforfatter: Perry, G.H.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920192/
https://ncbi.nlm.nih.gov/pubmed/19287166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000184719
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