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Molecular Organization of the Complex Between Muscarinic M3 Receptor and Regulator of G Protein Signaling Gβ(5)-RGS7

Regulator of G protein signaling (RGS) complex, Gβ(5)-RGS7, can inhibit signal transduction via the M3 muscarinic acetylcholine receptor (M3R). RGS7 consists of three distinct structural entities: the DEP domain and its extension DHEX, the G gamma like (GGL) domain, which is permanently bound to the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sandiford, Simone L., Wang, Qiang, Levay, Konstantin, Buchwald, Peter, Slepak, Vladlen Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920065/
https://ncbi.nlm.nih.gov/pubmed/20443543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100080p
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