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Microtubule-assisted mechanism for functional metabolic macromolecular complex formation

Evidence has been presented for a metabolic multienzyme complex, the purinosome, that participates in de novo purine biosynthesis to form clusters in the cytoplasm of living cells under purine-depleted conditions. Here we identified, using fluorescent live cell imaging, that a microtubule network ap...

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Autors principals: An, Songon, Deng, Yijun, Tomsho, John W., Kyoung, Minjoung, Benkovic, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919939/
https://ncbi.nlm.nih.gov/pubmed/20615962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008451107
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