Dynamic Regulation of a Metabolic Multi-enzyme Complex by Protein Kinase CK2

The reversible association and dissociation of a metabolic multi-enzyme complex participating in de novo purine biosynthesis, the purinosome, was demonstrated in live cells to respond to the levels of purine nucleotides in the culture media. We also took advantage of in vitro proteomic scale studies...

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Bibliografiske detaljer
Main Authors: An, Songon, Kyoung, Minjoung, Allen, Jasmina J., Shokat, Kevan M., Benkovic, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856985/
https://ncbi.nlm.nih.gov/pubmed/20157113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.101139
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