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Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway
While many functions of the p53 tumor suppressor affect mitochondrial processes, the role of altered mitochondrial physiology in a modulation of p53 response remains unclear. As mitochondrial respiration is affected in many pathologic conditions such as hypoxia and intoxications, the impaired electr...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919937/ https://ncbi.nlm.nih.gov/pubmed/20566882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910885107 |
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