Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance

The ESCRT pathway helps mediate the final abscission step of cytokinesis in mammals and archaea. In mammals, two early acting proteins of the ESCRT pathway, ALIX and TSG101, are recruited to the midbody through direct interactions with the phosphoprotein CEP55. CEP55 resides at the centrosome throug...

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Bibliografiske detaljer
Main Authors: Morita, Eiji, Colf, Leremy A., Karren, Mary Anne, Sandrin, Virginie, Rodesch, Christopher K., Sundquist, Wesley I.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919903/
https://ncbi.nlm.nih.gov/pubmed/20616062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005938107
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