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Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance

The ESCRT pathway helps mediate the final abscission step of cytokinesis in mammals and archaea. In mammals, two early acting proteins of the ESCRT pathway, ALIX and TSG101, are recruited to the midbody through direct interactions with the phosphoprotein CEP55. CEP55 resides at the centrosome throug...

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Detalhes bibliográficos
Main Authors: Morita, Eiji, Colf, Leremy A., Karren, Mary Anne, Sandrin, Virginie, Rodesch, Christopher K., Sundquist, Wesley I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919903/
https://ncbi.nlm.nih.gov/pubmed/20616062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005938107
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