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Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding

The ESCRT pathway mediates membrane remodeling during enveloped virus budding, cytokinesis, and intralumenal endosomal vesicle formation. Late in the pathway, a subset of membrane-associated ESCRT-III proteins display terminal amphipathic “MIM1” helices that bind and recruit VPS4 ATPases via their M...

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Detalhes bibliográficos
Main Authors: Kieffer, Collin, Skalicky, Jack J., Morita, Eiji, De Dominico, Ivana, Ward, Diane M., Kaplan, Jerry, Sundquist, Wesley I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586299/
https://ncbi.nlm.nih.gov/pubmed/18606141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.05.014
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