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Comparison of Aβ levels in the brain of Swedish APP(670, 671) and PS1(M146V) mutation carriers and patients with sporadic Alzheimer's disease

Mutations in presenilin (PS) and amyloid precursor protein (APP) genes are a major cause for early-onset familial Alzheimer disease (AD). We measured Aβ levels in the cortex of APPsw and PS1 (M146V) mutation carriers, sporadic AD (SAD) and non-demented individuals. Levels of insoluble and soluble Aβ...

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Bibliografische gegevens
Hoofdauteurs: Hellstrom-Lindahl, E., Viitanen, M., Marutle, A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919843/
https://ncbi.nlm.nih.gov/pubmed/19524115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2009.03.007
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