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Comparison of Aβ levels in the brain of Swedish APP(670, 671) and PS1(M146V) mutation carriers and patients with sporadic Alzheimer's disease
Mutations in presenilin (PS) and amyloid precursor protein (APP) genes are a major cause for early-onset familial Alzheimer disease (AD). We measured Aβ levels in the cortex of APPsw and PS1 (M146V) mutation carriers, sporadic AD (SAD) and non-demented individuals. Levels of insoluble and soluble Aβ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919843/ https://ncbi.nlm.nih.gov/pubmed/19524115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2009.03.007 |
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