Chronic BACE-1 Inhibitor Administration in TASTPM Mice (APP KM670/671NL and PSEN1 M146V Mutation): An EEG Study

Objective. In this exploratory study, we tested whether electroencephalographic (EEG) rhythms may reflect the effects of a chronic administration (4 weeks) of an anti-amyloid β-site amyloid precursor protein (APP) cleaving enzyme 1 inhibitor (BACE-1; ER-901356; Eisai Co., Ltd., Tokyo, Japan) in TAST...

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Publicat a:Int J Mol Sci
Autors principals: Lopez, Susanna, Del Percio, Claudio, Forloni, Gianluigi, Frasca, Angelisa, Drinkenburg, Wilhelmus H., Lizio, Roberta, Noce, Giuseppe, Ferri, Raffaele, Soricelli, Andrea, Stocchi, Fabrizio, Vacca, Laura, Bordet, Règis, Richardson, Jill C., Babiloni, Claudio
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730584/
https://ncbi.nlm.nih.gov/pubmed/33260655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239072
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