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The role of the universally conserved A2450–C2063 base pair in the ribosomal peptidyl transferase center
Despite the fact that all 23S rRNA nucleotides that build the ribosomal peptidyl transferase ribozyme are universally conserved, standard and atomic mutagenesis studies revealed the nucleobase identities being non-critical for catalysis. This indicates that these active site residues are highly cons...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919715/ https://ncbi.nlm.nih.gov/pubmed/20375101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq213 |
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