DEFICIENCY OF TELOMERASE ACTIVITY AGGRAVATES THE BLOOD-BRAIN BARRIER DISRUPTION AND NEUROINFLAMMATORY RESPONSES IN A MODEL OF EXPERIMENTAL STROKE

Epidemiology and genetic studies indicate that patients with telomere length shorter than average are at higher risk of dying from heart disease or stroke. Telomeres are located at the ends of eukaryotic chromosomes which demonstrate progressive length reduction in most somatic cells during aging. T...

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Detalhes bibliográficos
Main Authors: Zhang, Bei, Chen, Lei, Swartz, Karin R., Bruemmer, Dennis, Eum, Sung Yong, Huang, Wen, Seelbach, Melissa, Choi, Yean Jung, Hennig, Bernhard, Toborek, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919635/
https://ncbi.nlm.nih.gov/pubmed/20564349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22450
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