Inhibition of telomerase activity alters tight junction protein expression and induces transendothelial migration of HIV-1-infected cells

Telomerase, via its catalytic component telomerase reverse transcriptase (TERT), extends telomeres of eukaryotic chromosomes. The importance of this reaction is related to the fact that telomere shortening is a rate-limiting mechanism for human life span that induces cell senescence and contributes...

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Bibliographic Details
Main Authors: Huang, Wen, Rha, Geun Bae, Chen, Lei, Seelbach, Melissa J., Zhang, Bei, András, Ibolya E., Bruemmer, Dennis, Hennig, Bernhard, Toborek, Michal
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853419/
https://ncbi.nlm.nih.gov/pubmed/20139322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01126.2009
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