Polychlorinated Biphenyls Disrupt Blood–Brain Barrier Integrity and Promote Brain Metastasis Formation

BACKGROUND: Polychlorinated biphenyls (PCBs) comprise a ubiquitous class of toxic substances associated with carcinogenic and tumor-promoting effects as well as neurotoxic properties in the brain. However, the effects of PCBs on the development of tumor metastases are not fully understood. OBJECTIVE...

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Detalhes bibliográficos
Main Authors: Seelbach, Melissa, Chen, Lei, Powell, Anita, Choi, Yean Jung, Zhang, Bei, Hennig, Bernhard, Toborek, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2010
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854723/
https://ncbi.nlm.nih.gov/pubmed/20064788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901334
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