Structural studies of Helicase NS3 variants from Hepatitis C virus genotype 3 in virological sustained responder and non-responder patients

BACKGROUND: About 130 million people are infected with the hepatitis C virus (HCV) worldwide, but effective treatment options are not yet available. One of the most promising targets for antiviral therapy is nonstructural protein 3 (NS3). To identify possible changes in the structure of NS3 associat...

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Autors principals: Provazzi, Paola JS, Arcuri, Helen A, de Carvalho-Mello, Isabel Maria VG, Pinho, João Renato R, Nogueira, Maurício L, Palma, Mário S, Rahal, Paula
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919562/
https://ncbi.nlm.nih.gov/pubmed/20630078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-196
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