New insights regarding HCV-NS5A structure/function and indication of genotypic differences

BACKGROUND: HCV is prevalent throughout the world. It is a major cause of chronic liver disease. There is no effective vaccine and the most common therapy, based on Peginterferon, has a success rate of ~50%. The mechanisms underlying viral resistance have not been elucidated but it has been suggeste...

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Autors principals: Yamasaki, Lilian HT, Arcuri, Helen A, Jardim, Ana Carolina G, Bittar, Cintia, de Carvalho-Mello, Isabel Maria VG, Rahal, Paula
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271958/
https://ncbi.nlm.nih.gov/pubmed/22239820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-14
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