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Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response

BACKGROUND: The quasispecies nature of HCV may have important implications for viral persistence, pathogenicity and resistance to antiviral agents. The variability of one of the viral proteins, NS5A, is believed to be related to the response to IFN therapy, the standard treatment for infection. In t...

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Detalhes bibliográficos
Main Authors: Bittar, Cíntia, Jardim, Ana Carolina G, Yamasaki, Lilian HT, de Queiróz, Artur TL, Carareto, Claudia MA, Pinho, João Renato R, de Carvalho-Mello, Isabel Maria VG, Rahal, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838888/
https://ncbi.nlm.nih.gov/pubmed/20178583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-36
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