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Clinical Manifestations, Etiology, and Pathogenesis of the Hyper IgE Syndromes

Autosomal dominant Hyper IgE syndrome (AD-HIES) is a rare primary immunodeficiency characterized by eczema, recurrent skin and lung infections, elevated serum IgE, and various connective tissue, skeletal, and vascular abnormalities. Mutations in Signal transducer and activator of transcription 3 (ST...

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Main Authors: Freeman, Alexandra F., Holland, Steven M.
格式: Artigo
語言:Inglês
出版: 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919366/
https://ncbi.nlm.nih.gov/pubmed/19190525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e31819dc8c5
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