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Clinical Manifestations of Hyper IgE Syndromes
Over the last 4 years, three genetic etiologies of hyper IgE syndromes have been identified: STAT3, DOCK8, and Tyk2. All of these hyper IgE syndromes are characterized by eczema, sinopulmonary infections, and greatly elevated serum IgE. However, each has distinct clinical manifestations. Mutations i...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
IOS Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835387/ https://ncbi.nlm.nih.gov/pubmed/21178271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2010-0734 |
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