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Analysis of the DNA translocation and unwinding activities of T4 phage helicases

Helicases are an important class of enzymes involved in DNA and RNA metabolism that couple the energy of ATP hydrolysis to unwind duplex DNA and RNA structures. Understanding the mechanism of helicase action is vital due to their involvement in various biological processes such as DNA replication, r...

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Bibliografiske detaljer
Main Authors: Perumal, Senthil K., Raney, Kevin D., Benkovic, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919206/
https://ncbi.nlm.nih.gov/pubmed/20170733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.02.011
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