Autoactivation of Transforming Growth Factor β-activated Kinase 1 Is a Sequential Bimolecular Process

Transforming growth factor-β-activated kinase 1 (TAK1), an MAP3K, is a key player in processing a multitude of inflammatory stimuli. TAK1 autoactivation involves the interplay with TAK1-binding proteins (TAB), e.g. TAB1 and TAB2, and phosphorylation of several activation segment residues. However, t...

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Hlavní autoři: Scholz, Roland, Sidler, Corinne L., Thali, Ramon F., Winssinger, Nicolas, Cheung, Peter C. F., Neumann, Dietbert
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919138/
https://ncbi.nlm.nih.gov/pubmed/20538596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093468
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