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Autoactivation of Transforming Growth Factor β-activated Kinase 1 Is a Sequential Bimolecular Process
Transforming growth factor-β-activated kinase 1 (TAK1), an MAP3K, is a key player in processing a multitude of inflammatory stimuli. TAK1 autoactivation involves the interplay with TAK1-binding proteins (TAB), e.g. TAB1 and TAB2, and phosphorylation of several activation segment residues. However, t...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919138/ https://ncbi.nlm.nih.gov/pubmed/20538596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093468 |
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