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Myc Is Required for the Maintenance of Kaposi's Sarcoma-Associated Herpesvirus Latency
Myc is deregulated by Kaposi's sarcoma-associated herpesvirus (KSHV) latent proteins, but its role in KSHV latency is not clear. We found that Myc knockdown with RNA interference (RNAi) induced KSHV reactivation and increased the protein and mRNA levels of RTA, a key viral regulator of KSHV rea...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919007/ https://ncbi.nlm.nih.gov/pubmed/20573831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00244-10 |
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