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Myc Is Required for the Maintenance of Kaposi's Sarcoma-Associated Herpesvirus Latency

Myc is deregulated by Kaposi's sarcoma-associated herpesvirus (KSHV) latent proteins, but its role in KSHV latency is not clear. We found that Myc knockdown with RNA interference (RNAi) induced KSHV reactivation and increased the protein and mRNA levels of RTA, a key viral regulator of KSHV rea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Xudong, Chen, Shijia, Feng, Jun, Deng, Hongyu, Sun, Ren
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919007/
https://ncbi.nlm.nih.gov/pubmed/20573831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00244-10
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