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Myc Is Required for the Maintenance of Kaposi's Sarcoma-Associated Herpesvirus Latency
Myc is deregulated by Kaposi's sarcoma-associated herpesvirus (KSHV) latent proteins, but its role in KSHV latency is not clear. We found that Myc knockdown with RNA interference (RNAi) induced KSHV reactivation and increased the protein and mRNA levels of RTA, a key viral regulator of KSHV rea...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919007/ https://ncbi.nlm.nih.gov/pubmed/20573831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00244-10 |
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