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Myc Is Required for the Maintenance of Kaposi's Sarcoma-Associated Herpesvirus Latency

Myc is deregulated by Kaposi's sarcoma-associated herpesvirus (KSHV) latent proteins, but its role in KSHV latency is not clear. We found that Myc knockdown with RNA interference (RNAi) induced KSHV reactivation and increased the protein and mRNA levels of RTA, a key viral regulator of KSHV rea...

詳細記述

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書誌詳細
主要な著者: Li, Xudong, Chen, Shijia, Feng, Jun, Deng, Hongyu, Sun, Ren
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919007/
https://ncbi.nlm.nih.gov/pubmed/20573831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00244-10
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