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Myc Is Required for the Maintenance of Kaposi's Sarcoma-Associated Herpesvirus Latency

Myc is deregulated by Kaposi's sarcoma-associated herpesvirus (KSHV) latent proteins, but its role in KSHV latency is not clear. We found that Myc knockdown with RNA interference (RNAi) induced KSHV reactivation and increased the protein and mRNA levels of RTA, a key viral regulator of KSHV rea...

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Bibliographic Details
Main Authors: Li, Xudong, Chen, Shijia, Feng, Jun, Deng, Hongyu, Sun, Ren
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919007/
https://ncbi.nlm.nih.gov/pubmed/20573831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00244-10
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