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Cutting Edge: Responder T Cells Regulate Human DR(+) Effector Regulatory T Cell Activity via Granzyme

MHC class II expression identifies an effector subset of human CD4(+)CD25(high)FoxP3(high) natural regulatory T cells (DR(+) Tregs) that induces more rapid suppression and exhibits higher FoxP3 expression than the remaining Treg population. Although Tregs are known to be highly sensitive to apoptosi...

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Detalhes bibliográficos
Main Authors: Ashley, Charles W., Baecher-Allan, Clare
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918804/
https://ncbi.nlm.nih.gov/pubmed/19801510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900845
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