Spinal upregulation of glutamate transporter GLT-1 by ceftriaxone: therapeutic efficacy in a range of experimental nervous system disorders

Glutamate neurotransmission is highly regulated, largely by glutamate transporters. In the spinal cord, the glutamate transporter GLT-1 is primarily responsible for glutamate clearance. Downregulation of GLT-1 can occur in activated astrocytes, and is associated with increased extracellular glutamat...

Full description

Saved in:
Bibliographic Details
Main Authors: Ramos, Khara M., Lewis, Makenzie T., Morgan, Kelly N., Crysdale, Nicole Y., Kroll, Juliet L., Taylor, Frederick R., Harrison, Jacqueline A., Sloane, Evan M., Maier, Steven F., Watkins, Linda R.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918694/
https://ncbi.nlm.nih.gov/pubmed/20547213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.06.014
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items