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Intrinsically disordered proteins are potential drug targets
Intrinsically disordered (ID) proteins which lack stable secondary and tertiary structure in substantial regions (or throughout) are prevalent in eukaryotes. They exist as ensembles of rapidly fluctuating structures and many undergo coupled folding and binding reactions. Because ID proteins are over...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918680/ https://ncbi.nlm.nih.gov/pubmed/20598937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.06.169 |
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