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Intrinsically disordered proteins and biomolecular condensates as drug targets
Intrinsically disordered domains represent attractive therapeutic targets because they play key roles in cancer as well as in neurodegenerative and infectious diseases. They are however considered undruggable because they do not form stable binding pockets for small molecules and therefore have not...
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| Pubblicato in: | Curr Opin Chem Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7616887/ https://ncbi.nlm.nih.gov/pubmed/33812316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2021.02.009 |
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