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Ganglioside embedded in reconstituted lipoprotein binds cholera toxin with elevated affinity

The ability to exogenously present cell-surface receptors in high-affinity conformations in a synthetic system offers an opportunity to provide host cells with protection from pathogenic toxins. This strategy requires improvement of the synthetic receptor binding affinity against its native counterp...

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Bibliografski detalji
Glavni autori: Bricarello, Daniel A., Mills, Emily J., Petrlova, Jitka, Voss, John C., Parikh, Atul N.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918455/
https://ncbi.nlm.nih.gov/pubmed/20472870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M007401
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