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α-Cyclodextrin decreases cholera toxin binding to GM(1)-gangliosides
Cholera toxin (CT), the principal virulence factor secreted by Vibrio cholerae, is an A-B5 type exotoxin that binds to host cell GM1-gangliosides and is responsible for cholera diarrhoea. We tested the hypothesis that the cyclic hexasaccharide α-cyclodextrin (α-CD), but not the cyclic heptasaccharid...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for General Microbiology
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083513/ https://ncbi.nlm.nih.gov/pubmed/23538564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jmm.0.057232-0 |
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