Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice

ATP-citrate lyase (ACL) is a key lipogenic enzyme that converts citrate in the cytoplasm to acetyl-CoA, the initial precursor that yields malonyl-CoA for fatty acid biosynthesis. As cytosolic citrate is derived from the tricarboxylic acid cycle in the mitochondrion, ACL catalyzes a critical reaction...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Qiong, Li, Shoufeng, Jiang, Lei, Zhou, Yunhua, Li, Zi, Shao, Mengle, Li, Wenjun, Liu, Yong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2010
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918436/
https://ncbi.nlm.nih.gov/pubmed/20488800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M003335
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