Synthesis and evaluation of new endomorphin-2 analogues containing (Z)-α,β-didehydro-phenylalanine (Δ(Z)Phe) residues

New endomorphin-2 (EM-2) analogues incorporating (Z)-α,β-didehydro-phenylalanine (Δ(Z)Phe) in place of the native phenylalanine in EM-2 are reported. Tyr-Pro-Δ(Z)Phe-Phe-NH(2) {[Δ(Z)Phe(3)]EM-2} (1), Tyr-Pro-Phe-Δ(Z)Phe-NH(2) {[Δ(Z)Phe(4)]EM-2} (2) and Tyr-Pro-Δ(Z)Phe-Δ(Z)Phe-NH(2) {[Δ(Z)Phe(3,4)]EM...

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Detaylı Bibliyografya
Asıl Yazarlar: Torino, Domenica, Mollica, Adriano, Pinnen, Francesco, Feliciani, Federica, Lucente, Gino, Fabrizi, Giancarlo, Portalone, Gustavo, Davis, Peg, Lai, Josephine, Ma, Shou-Wu, Porreca, Frank, Hruby, Victor J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918392/
https://ncbi.nlm.nih.gov/pubmed/20476738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm1001343
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