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A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy

We describe a novel signaling mechanism mediated by the G-protein-coupled receptor (GPCR) angiotensin II (Ang II) type 2 receptor (AT(2)). Yeast two-hybrid studies and affinity column binding assay show that the isolated AT(2) C-terminus binds to the transcription factor promyelocytic zinc finger pr...

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Bibliografiska uppgifter
Huvudupphovsmän: Senbonmatsu, Takaaki, Saito, Takako, Landon, Erwin J., Watanabe, Otsu, Price, Edward, Roberts, Richard L., Imboden, Hans, Fitzgerald, Trinita G., Gaffney, F.Andrew, Inagami, Tadashi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC291832/
https://ncbi.nlm.nih.gov/pubmed/14657020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg637
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