S6K1 Plays a Critical Role in Early Adipocyte Differentiation

Earlier, we reported that S6K1(−/−) mice have reduced body fat mass, elevated rates of lipolysis, severely decreased adipocyte size, and are resistant to high-fat-diet (HFD)-induced obesity. Here we report that adipocytes of S6K1(−/−) mice on a HFD, have the capacity to increase in size to a degree...

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Bibliografiska uppgifter
Huvudupphovsmän: Carnevalli, Larissa S., Masuda, Kouhei, Frigerio, Francesca, Le Bacquer, Olivier, Um, Sung Hee, Gandin, Valentina, Topisirovic, Ivan, Sonenberg, Nahum, Thomas, George, Kozma, Sara C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918254/
https://ncbi.nlm.nih.gov/pubmed/20493810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.02.018
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