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Co-translational mechanisms of quality control of newly synthesized polypeptides
During protein synthesis, nascent polypeptides emerge from ribosomes to fold into functional proteins. Misfolding of newly synthesized polypeptides (NSPs) at this stage leads to their aggregation. These misfolded NSPs must be expediently cleared to circumvent the deleterious effects of protein aggre...
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| Publicat a: | Translation (Austin) |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705825/ https://ncbi.nlm.nih.gov/pubmed/26779401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trla.28109 |
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