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CombiClick™, Solid Support Based Combinatorial “Click Chemistry” for Efficient Oligonucleotide Conjugation: A New Versatile Method for Oligonucleotide Labeling
RP-73 The Copper (I) catalyzed Huisgen 1,3-dipolar cycloaddition between alkynes and azides discovered by the Sharpless group in 2002 (“click chemistry”), is a novel and very potent method for incorporation of molecules of interest (reporter molecules, lipophilic ligands, etc.) into oligonucleotides...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Association of Biomolecular Resource Facilities
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918035/ |
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