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CombiClick™, Solid Support Based Combinatorial “Click Chemistry” for Efficient Oligonucleotide Conjugation: A New Versatile Method for Oligonucleotide Labeling

RP-73 The Copper (I) catalyzed Huisgen 1,3-dipolar cycloaddition between alkynes and azides discovered by the Sharpless group in 2002 (“click chemistry”), is a novel and very potent method for incorporation of molecules of interest (reporter molecules, lipophilic ligands, etc.) into oligonucleotides...

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Hlavní autoři: Srivastava, N., Srivastava, S., Laikhter, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Association of Biomolecular Resource Facilities 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918035/
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