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Inhibition of HIV-1 Replication by Isoxazolidine and Isoxazole Sulfonamides
Targeting host factors is a complementary strategy for the development of new antiviral drugs. We screened a library of isoxazolidine and isoxazole sulfonamides and found four compounds that inhibited HIV-1 infection in human CD4+ lymphocytic T cells with no toxicity at IC(90) concentrations. Struct...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917890/ https://ncbi.nlm.nih.gov/pubmed/20486932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2010.00956.x |
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