Nicotinic Acetylcholine Receptor Transmembrane Mutations Convert Ivermectin from a Positive to a Negative Allosteric Modulator

Lignende værker

• The influence of allosteric modulators and transmembrane mutations on desensitisation and activation of α7 nicotinic acetylcholine receptors
  af: Chatzidaki, Anna, et al.
  Udgivet: (2015)
• Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization
  af: Collins, Toby, et al.
  Udgivet: (2011)
• Positive Allosteric Modulators of Nicotinic Acetylcholine Receptor
  af: Rosse, Gerard
  Udgivet: (2013)
• Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site
  af: Young, Gareth T., et al.
  Udgivet: (2008)
• Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor
  af: Smelt, Charles L.C., et al.
  Udgivet: (2018)