Lipid accumulation and dendritic cell dysfunction in cancer

Professional antigen presenting cells, dendritic cells (DC) are responsible for initiation and maintenance of immune responses. Here, we report that a substantial proportion of DCs in tumor-bearing mice and cancer patients have increased levels of triglycerides. Lipid accumulation in DCs was caused...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Herber, Donna L., Cao, Wei, Nefedova, Yulia, Novitskiy, Sergey V., Nagaraj, Srinivas, Tyurin, Vladimir A., Corzo, Alex, Cho, Hyun Il, Celis, Esteban, Lennox, Briana, Knight, Stella C., Padhya, Tapan, McCaffrey, Thomas V., McCaffrey, Judith C., Antonia, Scott, Fishman, Mayer, Ferris, Robert L., Kagan, Valerian E., Gabrilovich, Dmitry I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917488/
https://ncbi.nlm.nih.gov/pubmed/20622859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2172
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk