Lipid accumulation and dendritic cell dysfunction in cancer

Professional antigen presenting cells, dendritic cells (DC) are responsible for initiation and maintenance of immune responses. Here, we report that a substantial proportion of DCs in tumor-bearing mice and cancer patients have increased levels of triglycerides. Lipid accumulation in DCs was caused...

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Bibliografische gegevens
Hoofdauteurs: Herber, Donna L., Cao, Wei, Nefedova, Yulia, Novitskiy, Sergey V., Nagaraj, Srinivas, Tyurin, Vladimir A., Corzo, Alex, Cho, Hyun Il, Celis, Esteban, Lennox, Briana, Knight, Stella C., Padhya, Tapan, McCaffrey, Thomas V., McCaffrey, Judith C., Antonia, Scott, Fishman, Mayer, Ferris, Robert L., Kagan, Valerian E., Gabrilovich, Dmitry I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917488/
https://ncbi.nlm.nih.gov/pubmed/20622859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2172
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