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Uridine triphosphate (UTP) induces profibrotic responses in cardiac fibroblasts by activation of P2Y(2) receptors

Cardiac fibroblasts (CFs) play a key role in response to injury and remodeling of the heart. Nucleotide (P2) receptors regulate the heart but limited information is available regarding such receptors in CFs. We thus sought to determine if extracellular nucleotides regulate fibrotic responses (e.g.,...

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Detalhes bibliográficos
Main Authors: Braun, Oscar Ö., Lu, David, Aroonsakool, Nakon, Insel, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917486/
https://ncbi.nlm.nih.gov/pubmed/20471392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.05.001
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