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Isotope signatures allow identification of chemically crosslinked peptides by mass spectrometry: A novel method to determine interresidue distances in protein structures through crosslinking

Knowledge of protein structures and protein-protein interactions is essential for understanding of biological processes. Recent advances in protein crosslinking and mass spectrometry (MS) have shown significant potential to contribute to this area. Here we report a novel method to rapidly and accura...

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Detalhes bibliográficos
Main Authors: Zelter, Alex, Hoopmann, Michael R., Vernon, Robert, Baker, David, MacCoss, Michael J., Davis, Trisha N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917471/
https://ncbi.nlm.nih.gov/pubmed/20476776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr1001115
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