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High Speed Data Reduction, Feature Detection, and MS/MS Spectrum Quality Assessment of Shotgun Proteomics Datasets Using High Resolution Mass Spectrometry

Advances in Fourier transform mass spectrometry have made the acquisition of high-resolution and accurate mass measurements routine on a chromatographic time-scale. Here we report an algorithm, Hardklör, for the rapid and robust analysis of high resolution mass spectra acquired in shotgun proteomics...

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Detalhes bibliográficos
Main Authors: Hoopmann, Michael R., Finney, Gregory L., MacCoss, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556510/
https://ncbi.nlm.nih.gov/pubmed/17580982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac0700833
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