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Identification of a metalloprotease-chemokine signaling system in the ovarian cancer microenvironment: implications for anti-angiogenic therapy

Ovarian cancer is lethal gynecologic malignancy that may benefit from new therapies that block key paracrine pathways involved in tumor-stromal interactions and tumor vascularity. It was recently shown that matrix metalloprotease-1 (MMP-1) activation of the G protein-coupled receptor protease-activa...

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Main Authors: Agarwal, Anika, Tressel, Sarah L., Kaimal, Rajani, Balla, Marianthi, Lam, Francis H., Covic, Lidija, Kuliopulos, Athan
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917243/
https://ncbi.nlm.nih.gov/pubmed/20570895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4341
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